Gen-Shi Aridex belongs to the wide product range of Gen-Shi Labs, a reputed company due to their experience gained by being in the market for years. Gen-Shi Aridex contains 30 tablets of Anastrozole preparation.
Active-Life: 4-6 hours
Drug Class: Anti-estrogen /competitive inhibitor (Oral)
Average Reported Dosage: 0.5-3.0 mg daily
Water Retention: None
Liver Toxic: Yes dosage dependent
Decreases HPTA function: No, the drug has been accredited with HPTA up-regulating effects.
Anastrozole, better known by its trade name Arimidex, is an inhibitor of estrogens synthesis. As an aromatase inhibitor it can significantly minimize estrogen levels. While tamoxifen and clomiphene only block estrogen receptors, anastrozole prevents the conversion of testosterone.
Anastrozole is an important supplement for many bodybuilders who use steroids such as testosterone and Dianabol, or for those whose body is particularly predisposed and susceptible to estrogens effects (the endomorph type and those who can develop juvenile gynecomastia). Indeed, as previously said it acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen in the body (Arimidex has a 75-85% aromatization inhibition rate). This in turn prevents excessive estrogenic side effects during AAS use and helps developing a harder musculature for competitive bodybuilders.
Stacking 10-30 mg of Nolvadex with 1.0 mg of Arimidex has been reported to lead to almost no estrogen activity. However, keep in mind that some estrogens levels are required in order for some AAS to reach their full potential. Remember that estrogens play a role in stimulating the production of luteinizing hormone (LH), which, in turn, will stimulate testosterone production. They can also participate in the correction of lipid levels in the blood after a cycle, a point where anastrozole is not involved.
Arimidex has a very short active-life so 0.5 mg dosages can be taken 2 times daily or more at equal intervals.
Generally, it takes a week to the drug to make full effect. What is interesting is that anastrozole can be used in a cycle or in recovery: an elevation of testosterone levels up to 58% has been asserted when using Anastrozole as a testosterone booster.
Directly following an AAS cycle, the dosage will be reduced from a higher starting dosage to a low dosage to be continued for 7-14 days after AAS discontinuance.
Yes, although there could be some side effects for some people. For example, its use may increase liver enzymes, so people taking other hepatotoxic drugs should remember it. Then, the risk of bone fractures increases somewhat as the protective role of estrogen is no longer present. A phenomenon called "shin splints" occurs frequently. Anastrozole should not be taken by women without medical supervision. Fetal malformations were reported as a result of its use.
Note that pain and joint crunches have been reported when using this medication.